Skip to content
Friday 7 August 2026London --:--Frankfurt --:--Zurich --:--
NewslettersSearchEN · DE
MorningWire

European business, markets and politics

FTSE 100
10,867.89
-0.19%
DAX
26,140.13
0.00%
CAC 40
8,699.71
0.00%
STOXX 50
6,502.56
0.00%
  • Europe
  • Markets
  • Business
  • Economy
  • Technology
  • Politics
  • Opinion
More
GermanyFranceBankingAIEnergyFintechPropertyCapital Markets
  • Germany
  • France
  • Europe
  • Markets
  • Business
  • Economy
  • Technology
  • Politics
  • Opinion
  • DE
Monday 29 September 2025 1:03 pm  |  Updated:  Monday 29 September 2025 1:05 pm

Astrazeneca to ‘upgrade’ US listing in latest blow to London Stock Exchange

By: Simon Hunt

City Editor

Add as a preferred source on Google
Astrazeneca headquarters with logo, reflecting commitment to reduce US medicine prices after Trump administration pressure
Astrazeneca shareholders have questioned the possible merger

Astrazeneca has laid out plans aimed at “upgrading” its US listing in the latest blow to the London Stock Exchange.

The Cambridge-based pharma giant said it would replace its existing Nasdaq listing of American Depositary Receipts (ADRs), a type of listing for trading overseas shares, with a direct listing of ordinary shares on the New York Stock Exchange in a bid to give it “the flexibility to access the broadest possible available pool of capital.”

Following implementation of the new scheme, dubbed the Harmonised Listing Structure, shareholders will be able to trade Astrazeneca shares across the London Stock Exchange, Nasdaq Stockholm and the New York Stock Exchange, in a downgrade of London’s role as the principal trading venue for its shares.

But the company has recommitted to the UK, adding that it would continue to be listed, headquartered in and tax resident in Britain. The announcement also puts to bed rumours that the pharma firm had been plotting to delist from London altogether.

Astrazeneca chair Michel Demaré said: “Enabling a global listing structure will allow us to reach a broader mix of global investors and will make it even more attractive for all our shareholders to have the opportunity to participate in Astrazeneca’s exciting future.”

The move adds Astrazeneca to a growing number of UK firms that have pursued a US listing in search of improved liquidity and higher valuations. In June, £11bn London fintech Wise swapped London for New York as its primary listing venue, while in 2023, the Japanese owners of $150bn Cambridge-based semiconductor firm Arm, a former FTSE 100 constituent, opted to re-list the company in New York.

Neil Wilson, UK Investor Strategist at Saxo Bank, said Astrazeneca “wants to improve visibility and tap the deeper markets of the US while retaining its British and Swedish DNA. 

Read more

Astrazeneca explores $400bn megadeal with US rival 

AstraZeneca building exterior with logo, glass facade, UK flag, and wildflowers in foreground.

“I think there is probably relief that it’s not pursuing a primary listing in New York, but the decision is hardly a ringing endorsement of London. 

“It reflects the fundamental, structural issues in the UK for the largest globally-oriented stocks – the depth and liquidity of its capital markets is falling short of what’s on offer across the pond.”

Pivot to the US

The decision is the latest sign that Astrazeneca is eyeing the US as its fastest driver of growth in the coming years as the pharma firm pares back investment in the UK.

In July, the company unveiled plans to invest as much as $50bn in manufacturing and R&D in the US over the next five years. 

The investment is set to include a new manufacturing facility in Virginia, its largest-ever single manufacturing investment, as well as manufacturing facilities for cell therapy in Rockville, Maryland and Tarzana, California, as well as a new R&D centre in Cambridge, Massachusetts.

Earlier this month, however, Astrazeneca paused a planned £200m expansion of its research site in Cambridge, while earlier this year it abandoned plans to invest £450 million in a vaccine plant in Merseyside.

Read more

Astrazeneca share price tumbles on $400bn megamerger talks

Astrazeneca headquarters with logo, reflecting commitment to reduce US medicine prices after Trump administration pressure

Share this article

  • Facebook
  • X
  • LinkedIn
  • WhatsApp
  • Email

Similarly tagged content:

Sections

  • News

Categories

  • Business

People & Organisations

  • Astrazenaca
  • London Stock Exchange
  • LSE
  • Nasdaq
  • pharmaceuticals
  • UK economy
  • UK Government

Trending Articles

  • Donald Trump is creeping towards a shrewd sanctions policy

  • Rupert Lowe axes pensions triple lock and pledges tax cuts in economic plan

  • West Ham: Staveley receives Sadiq Khan encouragement to buy London Stadium

  • North Sea is not competitive, says BP boss days after exit

  • Luke Combs, Wembley review: as personal as a Texas honky-tonk

More from Morning Wire

  • Astrazeneca explores $400bn megadeal with US rival 

    Markets
    AstraZeneca building exterior with logo, glass facade, UK flag, and wildflowers in foreground.
  • Astrazeneca share price tumbles on $400bn megamerger talks

    Investing
    Astrazeneca headquarters with logo, reflecting commitment to reduce US medicine prices after Trump administration pressure
  • Glencore targets secondary listing in Australia as London loses mining shine

    Mining
    Glencore corporate headquarters building exterior with the company logo sign, representing the commodities firm.
  • Fresh tech sell-off fears as investor chip frenzy cools

    Markets
    Private Credit
  • Wise denied US banking licence in blow to expansion plans

    Banking
    Wise outlined plans to shift its primary listing to the US in June.
  • London’s IPO lull expected to last into 2027

    Markets
    The London Stock Exchange has had a challenging 2024 so far, although bankers are eying a rebound for IPOs
  • British brewery drafts plan to join Pisces platform

    Markets
    King Charles III pulls a pint at Wadworth Brewery with brewery staff, showcasing beer taps.
  • If Burnham wants growth he’ll have to save the City

    Business
    London Stock Exchange building exterior on a busy trading day with bustling city atmosphere and iconic architecture
MorningWire

Independent European business, markets and political news for decision-makers.

Morning Briefing

Europe

  • Germany
  • France
  • Europe
  • UK & Ireland

Business

  • Markets
  • Banking
  • Technology
  • Energy
  • Property
  • Fintech

Editorial

  • Opinion
  • Editorial Policy
  • Corrections
  • Contact

Company

  • About Morning Wire
  • Privacy Policy
  • Terms of Use
  • Cookie Policy
© 2026 Morning Wire Ltd · Published by Morning Wire Media, Bahnhofstrasse 65, 8001 Zürich, Switzerland
Privacy · Terms · Cookies · Facebook